A city of charming canals, elegant gabled houses, splendid museums and abundant bicycles, the Dutch capital of Amsterdam is a delight to explore. Its patchwork of waterways forms about 90 islands connected by 1,500 bridges. The legacy of the Dutch Golden Age lives on in gilded manses and in the lush paintings of Rembrandt and other Dutch masters that adorn the Rijksmuseum, The Netherlands' grand repository of art and cultural history. Discovering Amsterdam is a pleasure best pursued on foot; visitors line the tranquil canals and linger over Dutch pancakes, or take a stroopwafel to go.

Sail the bucolic waters of the Rhine, deep into the Rhine–Meuse–Scheldt Delta, as classic Dutch landscapes unfurl all around. Flat farmland, charming windmills and svelte poplar trees line the shores, and vast tracts of land stretch in all directions, growing all manner of bounty, from tomatoes to tulips. Gaze upon Friesian cows and tidy villages with their neatly laid farmhouses and marvel at how much of this land was reclaimed from the sea, with the aid of traditional windmills and the construction of dikes.

Cologne reveals its Roman heritage in its city layout and the ancient ruins that lie scattered through the town. Cologne's modern plazas and Hohe Strasse host welcoming shops, enticing restaurants and cologne boutiques. Of note is the city's 13th-century cathedral, a stunning example of Gothic artistry and a UNESCO World Heritage Site. Having survived Allied bombs during World War II, the cathedral's imposing twin spires are visible for miles and its stained glass windows fill the interior with brilliant colored light. Its steps lead to a platform with astounding views.

The Rhine River flows through one of Germany's most scenic regions. As you sail its most picturesque stretch, the UNESCO World Heritage Site of the Middle Rhine, you will pass vineyard-blanketed hills whose steep slopes require vintners to pick grapes by hand, keeping a centuries-old tradition alive. Splendid castles line the banks, all of which have stories to share, and the Lorelei Rock presides at a dramatic curve in the river. This infamous river maiden mesmerized sailors with her song and lured them to their demise at her feet.

The quiet German town of Speyer lies on the west bank of the Rhine. The city features a Romanesque imperial cathedral, burial place of eight emperors including some of the most famous Holy Roman Emperors. Speyer was once a major Celtic center that traded hands several times between the Romans and the Huns. The term Protestant originated here at the Diet of Speyer in 1529, when 14 free cities of Germany and six Lutheran princes protested the Edict of Worms that had banned the writings of Martin Luther and labeled him a heretic and enemy of the state.

The largest port on the Upper Rhine, Strasbourg is the cultural center of France's Alsace region. Thanks to its location at the border of France and Germany, it boasts a convivial mix of cultural influences. The well-preserved old town is enclosed on all sides by the little Ill River, with sites so compact that it is easy to explore the "island” on foot. And there is plenty to explore: cobblestone streets lined with wooden houses and intersected by picturesque canals. Indulging in Alsatian café culture is central to any visit here; enjoy coffee and cake amid lovely half-timbered houses.

Breisach is a gateway to the fabled Black Forest region, built on a basalt rock outcropping in the Rhine plain. It is located in one of the warmest parts of Germany, across the river from French Alsace, famous for its wine growing. But Breisach, too, can boast about its wine: it is home to Europe's largest cellars, with a storage capacity of more than 160 million liters. The most prominent landmark of Breisach is the Romanesque-Gothic St. Stephen's Cathedral, built between the 12th and 13th centuries. Its two towers are visible from throughout the city and from the Rhine.

For oenophiles, all roads lead to Burgundy, and one road in particular-the Route des Grands Crus-is the address of eight of the ten most expensive wines in the world. Sublime as it is, its wine tells only part of Burgundy's story. This serene region is French culture personified, where farmers and vintners are as respected as the harvests they produce. While the region's rolling hills are known for their superior wines and amazing cuisine, Burgundy's villages are celebrated for their tranquil beauty and historical heritage.

Lyon is known as the food capital of France. It is not uncommon for well-heeled Parisians to travel to Lyon for dinner. The city is surrounded by towns and villages that produce excellent fresh produce, and gastronomic outlets are plentiful here. The great chefs of Lyon enjoy celebrity status, whether they prepare classic recipes the traditional way or elevate them with their own signature touches. Their delicious meals may be paired with a glass of light, fruity Beaujolais from the north or a bold Rhône red from the south.

One of Europe's densest concentrations of urban Renaissance buildings, Old Lyon is pure pleasure to explore. The dwellings of this UNESCO site date back to the city's silk weaving success during the 15th century, when Italian merchants and bankers put their profits into building town houses; today some of their elegant residences house museums. St. Jean Cathedral lies in the heart of Old Lyon and is a stunning example of Romanesque and Gothic architecture. It has weathered periods of political turmoil and religious wars and is now one of the city's most prominent symbols.

Situated in France's Côtes du Rhône region, Vienne is the gateway to Lyon's countryside. It is one of the oldest towns in France, with a history that can be traced through its architecture. Among its Roman remains and artifacts, the Roman Temple of Augustus & Livia dates back to the 1st century AD. Its Roman amphitheater, nestled in the hills of Mont Pipet, is one of the best preserved in the nation. Vienne also boasts remarkably preserved medieval buildings and market ruins. Other landmarks include the Abbey of Saint Pierre and the Church of Saint-André-le-Bas.

Tournon lies secluded between the river and the vineyard-blanketed granite slopes that nurture fine vintages. An ancient castle, built snugly into a rock, overlooks the riverside setting. A settlement has perched on this hill since Celtic times, but the stunning views from its overlook have never changed. The name of its neighboring wine-producing region, Tain-l'Hermitage, comes from the hermit who planted vines here after returning from the Crusades. Today, his vines are awash in sunshine and produce a port-like wine and some stellar whites.

In the last days of the Roman Empire, Arles was the capital of Roman Gaul and boasts many Gallo-Roman ruins including Les Arènes; this ancient amphitheater seats 20,000 and is still used today for bullfights and plays. The town has an energetic feel, attracting farmers from the countryside to the frequent and famous Provençal market. It also enjoys a rich artistic heritage; the Mediterranean sunlight here inspired legendary Impressionist Vincent van Gogh to paint a number of works. Many of Arles's sights are immortalized in his paintings.

Avignon's narrow streets are lined with churches and remarkable medieval buildings. This "City of Popes” was the papal seat for 70 years during the 14th century after the sitting pope abandoned Rome and fled here. The massive church-fortress Palais des Papes, or Palace of the Popes, was the center of the Christian world during that controversial period. It remains a work of Gothic splendor. Another of Avignon's notable structures reaches into the Rhône, the ruins of the Pont d'Avignon. The 12th-century bridge, immortalized in folk song and dance, once spanned the river.

Bid farewell to your fellow guests and journey home. Or spend more time exploring, perhaps joining one of our extensions.